Unlock Ada Wong:
In game type A score 4000 or more points or alternately hit all of the targets on game type A.

Unlock Bella Sisters:
On game type B score 4000 or more points or alternately hit all of the targets on game type B.

Unlock Don Pedro:
In game type C Score 4000 or more points or alternately hit all of the targets on game type C.

Unlock J.J:
In game type D score 4000 or more points or Hit all the targest in game D except Ashley.

Unlock Ashley Graham:
In game type A score 3000 or more points.

Unlock Leon with Rocket Launcher:
In game type A Score 3000 or more points.

Unlock Leon with Shotgun:
In game type A score 3000 or more points.

Unlock Leon with Handgun:
In game type A score 3000 or more points.

Unlock Luis Sera:
In game type A score 3000 or more points.

Unlock Don Diego:
In game type B score 3000 or more points.

Unlock Don Esteban:
In game type B score 3000 or more points.

Unlock Don Jose:
In game type B score 3000 or more points.

Unlock Don Manuel:
In game type B score 3000 or more points.

Unlock Dr. Salvador:
In game type B score 3000 or more points.

Unlock Zealot with Bowgun, Zealot with Scythe, Zealot with Shield:
In game type C score 3000 or more points

Unlock Leader Zealot:
In game type C score 3000 or more points.

Unlock Merchant:
In game type C score 3000 or more points.

Unlock Isabel:
In game type D score 3000 or more points.

Unlock Maria:
In game type D score 3000 or more points.

Unlock Soldier with Dynamite, Soldier with Hammer, Soldier with Stun-rod:
In game type D score 3000 or more points.

Other Unlockables

Unlock Special Clothes for Ada, Leon and Ashley:
Beat the main game. Unlock

Alternate Title Screen:
Complete the main game once.

Unlock Seperate Ways (Bonus Game):
Beat the main game once.

Unlock Ashley’s Knight Armor Outfit:
Beat Seperate Ways.

Unlock Leon’s Gangster Outfit:
Beat Seperate Ways.

Unlock Chicago Typewriter (Main Game):
Beat Seperate Ways.

Unlock Chicago Typewriter (Seperate Ways):
Beat Assignment Ada.

Unlock Handcannon:
Have each mercenary get a five star rating on all of the stages.

Unlock Professional Difficulty Setting:
Beat the main game once.

Unlock Plagas Laser Cannon:
Beat the game on Professional difficulty setting.

Unlock P.R.L 412:
Beat Professional difficulty setting

Unlock Infinite Rocket Launcher:
Beat the game once.

Unlock Matilda:
Beat the game once.

Unlock Mercenaries:
Beat the main game once.

Unlock Movie Browser:
Beat the game

Mercenaries Mode unlockables

Unlock Ada:
Beat the Pueblo level with a 4 Star rank

Unlock Albert Wesker:
Beat the Waterworld with a 4 Star rank

Unlock Jack Krauser:
Beat the Castle with a 4 Star rank

Unlock Hunk:
Beat the Commando Base with a 4 Star rank

Unlock Handcannon:
Get 5 Star rankings on All levels with All the characters